In the field of brain-computer interface, Precision Neuroscience has implanted more than 4,096 electrodes into a human brain— breaking the world record and exceeding the previous record of 2,048 electrodes established in the previous year.
More electrodes mean more information. The data transferred to the brain and back is getting amplified by additional electrode numbers that have significantly enhanced the interface system’s capabilities. This breakthrough happened in April 2024 as part of a trial conducted at Mount Sinai Health System in New York — testing Precision Neuroscience’s implant. The company introduced its Layer 7 Cortical Interface, which is a thin film microelectrode array designed to match the brain’s cortex structure without any harm to the surrounding tissues.
With the proprietary minimally invasive insertion process from Precision Neuroscience, thousands of channels can be inserted into any part of the brain. A unique hardware interface is linked to 1,024 electrodes with diameters varying from 50 to 380 microns per microelectrode array.
“Advanced brain–computer interfaces require collecting and processing large amounts of neural data, potentially spanning multiple brain regions. Our Layer 7 Cortical Interface provides these capabilities while prioritizing patient safety,” stated Precision Neuroscience.
When the brain processes information or initiates an action, it generates electrical signals. Precision’s thin film technology can capture these signals at a micron scale, offering an unprecedented view into the brain’s activity, akin to shifting from standard to high-definition television.
“It is easy to see the impact that high-resolution cortical mapping could have in the operating room. It could be used to guide more precise and efficient procedures, potentially leading to better outcomes for patients,” said Dr. Joshua B. Bederson, chair of Neurosurgery for the Mount Sinai Health System, who led the study. The team placed four of Precision’s arrays onto the surface of a patient’s brain, covering an area of approximately 8 square cm with electrodes. Precision’s system streamed cortical data from all four arrays, generating a detailed visualization of the brain’s motor-sensory boundary—a critical landmark that neurosurgeons must navigate during surgery.
Founded in 2021 by a four-person team, three of whom previously worked at Neuralink, Precision Neuroscience has made significant strides. “Since then, we’ve developed our core product, the high-resolution cortical surface array, the Layer 7 Cortical Interface, and begun manufacturing it in a facility that we own and control. We’ve started testing our device in patients and are currently expanding our clinical presence. We anticipate having our first commercial product on the market in 2025,” stated the company.